A Cost-Effectiveness Analysis of an Adjuvanted Subunit Vaccine for the Prevention of Herpes Zoster and Post-Herpetic Neuralgia
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منابع مشابه
A health economic model for evaluating a vaccine for the prevention of herpes zoster and post-herpetic neuralgia in the UK
BACKGROUND A live-attenuated vaccine aimed at preventing herpes zoster (HZ) and its main complication, post-herpetic neuralgia (PHN) is available in Europe for immunocompetent adults aged 50 years and more. The study objective is to assess the cost effectiveness of a vaccination program for this population in the UK. METHODS A state-transition Markov model has been developed to simulate the n...
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Post herpetic neuralgia is a chronic neuropathic pain syndrome that it is characterized by pain in the area of the nerve involved distribution after the disappearance of herpes zoster lesions and it may be persistent, refractory and severe. Various treatments including medication, Botox injections, nerve block and physical modalities have been used in the treatment of this syndrome, each has ...
متن کامل[Herpes zoster and post-herpetic neuralgia in the elderly: Particularities in prevention, diagnosis, and treatment].
Herpes zoster (HZ) results from the reactivation of the varicella zoster virus latent in the sensory ganglia when cell-mediated immunity is altered. It is a frequent condition in older adults, leading to undesirable adverse outcomes. Aging is its main risk factor and the elderly may have different clinical presentations: zoster sine herpete, and a higher incidence of post-herpetic neuralgia (15...
متن کاملEpidemiological features and costs of herpes zoster in Taiwan: a national study 2000 to 2006.
To analyse the epidemiological characteristics and related costs of herpes zoster in Taiwan, a nationally representative cohort of 1,000,000 individuals from the National Health Insurance register was followed up from 2000 to 2006 and their claims data analysed. Overall, 34,280 patients were diagnosed with zoster (incidence 4.89/1000 person-years) and 2944 patients (8.6%) developed post-herpeti...
متن کاملEconomic evaluation of a vaccine for the prevention of herpes zoster and post-herpetic neuralgia in older adults in Switzerland.
BACKGROUND A life-attenuated vaccine aimed at preventing herpes zoster (HZ) and its main complication, post-herpetic neuralgia (PHN), will soon be available in Europe. The study's objective was to assess the clinical and economic impact of a vaccination program for adults aged 70-79 years in Switzerland. RESULTS A vaccination strategy compared to a no-vaccination resulted in lifetime incremen...
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